Hydroxypropyl beta cyclodextrin/HPBCD molecular weight with good solubility
Post Date:
Jul 05,2018
Expiry Date:
Jul 12,2018
Detailed Description:
Cas No. :128446-35-5
Price:30-60 USD Metric Tons
Hydroxypropyl beta cyclodextrin; HPBCD; HPCD
CAS No.: 94035-02-6
M.F. :C42.(H)70-n.O35.(C3H7)n
M.W. :1431-1806Standards: USP38,EP8.4,BP2015,CP2015
Grade: Oral or Injection
Storage:Preserved in well-closed containers
Shelf life : 2 years when properly stored.
Package:1kg/bag,25kg/drum.Or it's at your option .
Product Introduction
Hydroxypropyl-β-cyclodextrin (HP-β-CD) is the hydroxyalkylated derivatives of β- cyclodextrin (β-CD). HP-β-CD is non-toxic and has no side effect, and it can significantly improve the solubility of insoluble drugs to dissolve insoluble or poorly water-soluble drugs due to its structural particularity. Therefore, it can effectively increase bioavailability of drugs; it can also improve drug quality and variety of dosage forms, thereby being applied in development and production of new drugs. Globally, in-depth studies of the properties, preparation technology, stability, pharmacology, toxicology, teratogenic, mutagenic, carcinogenic, hemolysis, irritation and other aspects of HP-β-CD have already been performed; the safety of this drug has been evaluated accurately. Among all the derivatives of β-CD, HP-β-CD is considered as a type of pharmaceutical excipients with most complete research data and highest medicinal value, and it has been studied in-width and in-depth mostly.
Product Application
1:Medical use of hydroxypropyl β-cyclodextrinDue to the low surface activity, low hemolytic activity and non-irritation to muscles, Hydroxypropyl β-cyclodextrin is considered an ideal pharmaceutical excipient and solubilizer in injections in pharmaceutical industry. It works to solubilize water-insoluble drugs, enhance drug stability, improve drug bio-availability (improve efficacy or lower dosage of drugs), moderate and control drug release, and can also help to diminish the toxicity and side effects of drugs. Further, Hydroxypropyl β-cyclodextrin can be applied as a drug carrier in oral medications, injections, mucosal drug delivery system, transdermal drug delivery system, and targeted lipophilic drugs. Also, it is suitable as a protectant and stabilizer for proteins.2:Household chemicalsAs a stabilizer, emulsifier and scent masking agent, hydroxypropyl β-cyclodextrin can minimize the irritation to skin and mucous membranes resulting from the organic molecules in cosmetics. Additionally, it enhances the stability of active ingredients, protects nutrients against vaporization and oxidation, solubilizes insoluble fragrance and sustains the release of the fragrance to keep it long-lasting.3: Food industryHydroxypropyl β-cyclodextrin can improve the stability and long-acting efficacy of food nutrients while covering or counteracting the unpleasant smells and tastes. By using hydroxypropyl β-cyclodextrin, the manufacturing process and product quality can be improved and the shelf period can be prolonged.4. Other sectorsHydroxypropyl β-cyclodextrin has been widely used in many sectors including coating and painting products, tobacco products, pesticide excipients, plant growth regulators for agricultural use, paper industry, textile industry, et al. As people are gaining great awareness of hydroxypropyl β-cyclodextrin, it shows great promise and is used in more and more fields.