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Loperamide hydrochloride

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  Post Date: Mar 24,2014
  Expiry Date: Mar 24,2015
  Detailed Description: Cas No. :34552-83-5 Quantity: 50000Kilograms
Loperamide hydrochloride
Synonyms: Lopemin; Loperamide HCl
CAS: 34552-83-5
EINECS: 252-082-4
Assay: 99% min.
Standard: BP/EP/USP
Packing: 1kg/foil bag; 5kg/drum.
Character: White Solid.
Usage: used as an antidiarrheal, treatment of diarrhea.
Biological Activity: High affinity μ -opioid receptor agonist with peripheral selectivity (K i values are 2, 48 and 1156 nM for μ -, δ - and κ -opioid receptors respectively). Antidiarrhoeal and antihyperalgesic agent. Also a Ca 2+ channel blocker; at low micromolar concentrations it blocks broad spectrum neuronal HVA Ca 2+ channels and at higher concentrations it reduces Ca 2+ flux through NMDA receptor operated channels.
Gastrointestinal Agents:
Omeprazole
Ufiprazole
Pantoprazole Sodium
Pantoprazole intermediate
Esomeprazole Sodium
Esomeprazole Magnesium
Ursodeoxycholic acid
Ricobendazole
Loperamide HCl

  CAS Registry Number:

34552-83-5

  Synonyms: ;4-(4-(p-Chlorophenyl)-4-hydroxy-1-piperidyl)-N,N-dimethyl-2,2-diphenylbutyramide HCl;4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidine butyramide HCl;4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutyramide monohydrochloride;BLOX;BREK;Dissenten;Fortasec;Imodium;Imodium A-D;Imodium A-D EZ chews;Imosec;Lopemid;Lopemin;Loperamide HCl;Loperyl;Maalox Antidiarrheal;PJ185;R 18553;Suprasec;Tebloc;UNII-77TI35393C;Up and up anti diarrheal;1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-, hydrochloride;1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-, monohydrochloride;4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenylpiperidine-1-butyramide monohydrochloride;4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide hydrochloride (1:1);
  Molecular Formula: C29H34Cl2N2O2
  Molecular Weight: 513.4985
  Molecular Structure: 34552-83-5 loperamide hydrochloride
  Hazard Symbols:  T:Toxic;
  Risk Codes: R25:;
  Safety Description: S45:;

  Company: Hubei Yuancheng Pharmaceutical Co.,Ltd     [ China ]        
  Contact: Jane Dong
  Tel: +86-27-68886737
  Fax: +86-27-88048077-995
  Email: ycgsales01@yccreate.com
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