Ixabepilone
-
- Category :
Pharmaceuticals and Biochemicals
- CAS NO : 219989-84-1
- EC NO :
- Molecular Formula : C27H42N2O5S
- Main Specifications :
- Synonyms : (1R,5S,6S,7R,10S,14S,16S)-6,10-Dihydroxy-1,5,7,9,9-pentamethyl-14-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-13-azabicyclo[14.1.0]heptadecane-8,12-dione;(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-methyl-2-(2-methyl-1,3-thiazol-4-yl)ethenyl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione;
Package: According to customer's request
Uses : a semisynthetic analogue of epothilone B with antineoplastic activity
Molecular Structure:
Product description:
Introduction
Product Name Ixabepilone
CAS No. 219989-84-1
Synonyms BMS-247550; BMS247550; BMS 247550; Azaepothilone B; (1R,5S,6S,7R,10S,14S,16S)-6,10-Dihydroxy-1,5,7,9,9-pentamethyl-14-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-13-azabicyclo[14.1.0]heptadecane-8,12-dione; (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-((Z)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione
Molecular Formula C27H42N2O5S
Molecular Weight 506.70
MDL MFCD04307791
InChI 1/C27H42N2O5S/c1-15-9-8-10-27(7)22(34-27)12-20(16(2)11-19-14-35-18(4)28-19)29-23(31)13-21(30)26(5,6)25(33)17(3)24(15)32/h11,14-15,17,20-22,24,30,32H,8-10,12-13H2,1-7H3,(H,29,31)/b16-11+/t15-,17+,20-,21-,22-,24-,27+/m0/s1
Appearance White powder
Property*
Purity 99 %
Boiling Point (760 mmHg) 697.8 °C
Density 1.22 g/cm3
Flash Point 375.8 °C
*The values provided are general information and not part of the product specification.
Application
Main Applications Ixabepilone is an orally bioavailable microtubule inhibitor. Ixabepilone is a semisynthetic analogue of epothilone B with antineoplastic activity.
Packaging and Handling
Grade Pharma Grade
Packaging According to customer's request
Storage and Transportation Storage in original sealed container. Recommended storage temperature: -20 °C. Protect from moisture, heat and foreign material.
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