Afatinib
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- Category :
Pharmaceuticals and Biochemicals
- CAS NO : 439081-18-2
- EC NO :
- Molecular Formula : C24H25ClFN5O3
- Main Specifications : 99 %
- Synonyms : BIBW 2992;BIBW-2992;Tovok;2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)-;(2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide;Afatinib;(E)-N-(7-((S)-tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;BIBW2992;(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-dime;
Package: According to customer's request
Uses : Afatinib is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity.
Molecular Structure:
Product description:
Introduction
Product Name Afatinib
CAS No. 439081-18-2
Synonyms BIBW 2992; BIBW-2992; Tovok; N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; (2E)-N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide; (E)-N-(7-((S)-Tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide; 2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)-
Molecular Formula C24H25ClFN5O3
Molecular Weight 485.94
MDL MFCD12407405
InChI 1/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1
Appearance White to off-white solid powder
Property*
Purity 99 %
Boiling Point (760 mmHg) 676.9 °C
Density 1.381 g/cm3
Flash Point 363.2 °C
*The values provided are general information and not part of the product specification.
Application
Main Applications Afatinib is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity.
Packaging and Handling
Grade Pharma Grade
Packaging According to customer's request
Storage and Transportation Storage in original sealed container. Recommended storage temperature: -20 °C. Protect from moisture, heat and foreign material.
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