Home > Offer to Sell > Pharmaceuticals and Biochemicals > Central nervous system depressants and stimulants > Coluracetam
Coluracetam
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| Post Date: | May 26,2015 |
| Expiry Date: | May 25,2016 |
| Detailed Description: |
Cas No. :135463-81-9
Product name:Coluracetam
Chemical name: N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide. CAS:135463-81-9 Purity: 99% Appearance: white crystalline powder Package: 1kg/bag. Coluracetam (BCI-540) is a nootropic drug of the racetam family.Coluracetam (formerly known as MKC-231) was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California.Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD).BrainCells Inc is currently out-licensing the drug for this purpose.It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury. Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system. |
| CAS Registry Number: | 135463-81-9 |
| Synonyms: | N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide |
| Molecular Formula: | C19H23N3O3 |
| Molecular Weight: | 341.4042 |
| Molecular Structure: | 
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| Company: | Suzhou MyLand Pharm&Nutrition Inc. [ China ] |
| Contact: | Gledon fan |
| Tel: | 0512-66150687 |
| Fax: | -13771770578 |
| Email: | info@mylandpharm.com |
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